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The Guadalupe River in Seguin which is below Meadow Lake dam is a less active section of the Guadalupe River compared to the 23 mile section in the New Braunfels area.  This section of River is located about 20-40 minutes outside of New Braunfels. Real Estate along the Guadalupe River in Seguin is VERY affordable. Waterfront homes start under 200K, and they typically sell quickly.  If you are looking to kayak, swim, or just to enjoy the peaceful sounds and views of the Guadalupe River, then the Seguin area is for you. If you are interested in Guadalupe River homes for sale in Seguin and don’t see what you are looking for then click the green “Save This Search” button below to be automatically notified when new listings hit the market (no junk email) or have us sign you up.